Antibodies in sperm

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If you are struggling to get pregnant, it is important to consider both female and male factor infertility. As a result, the immune system will produce antisperm antibodies to destroy the sperm. If enough of these antibodies come into contact with the sperm, it can be difficult, if not impossible, for sperm to fertilize an egg. When a couple has difficulty getting pregnant due to antisperm antibodies, it is known as immunologic infertility.
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Antisperm antibodies

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Antisperm Antibody Test | Michigan Medicine

Certain men and certain women develop sperm antibody activity, and this can be demonstrated in the blood serum; in many cases, this activity can also be shown in the genital secretion. Unable to display preview. Download preview PDF. Skip to main content.
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Antisperm Antibody Test

Jump to content. An antisperm antibody test looks for special proteins antibodies that fight against a man's sperm in blood, vaginal fluids, or semen. The test uses a sample of sperm and adds a substance that binds only to affected sperm. Semen can cause an immune system response in either the man's or woman's body. The antibodies can damage or kill sperm.
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Study record managers: refer to the Data Element Definitions if submitting registration or results information. Corticosteroids have been indicated to treat men with ASAs. Although many studies have confirmed the clinical therapeutic significance of corticosteroids in the treatment of men with ASAs, other studies have not found a therapeutic significance for corticosteroids in the treatment of men with ASAs.
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